Loss of innervation of pancreatic islets associated with type 1 diabetes but not type 2 diabetes by Adam Burrack, PhD As our readers are aware, type 1 diabetes occurs because beta cells are destroyed by the immune system. This is the basic pathology underlying type 1 diabetes. Since beta cells are the only cells which […]
Saturday Morning Research Review – June 4, 2016
Mitochondrial dysfunction is related to Insulin Resistance in T1 youth. A recent article in the journal Diabetes shows that mitochondrial dysfunction is associated with insulin resistance in youth with type 1 diabetes. This research, conducted by Dr. Melanie Cree Green at the University of Colorado, gives us one more reason to pursue exercise as adjunct therapy for […]
Saturday Morning Research Review – May 28, 2016
The importance of glucagon for blood glucose level maintenance by Adam Burrack, PhD As any diabetic who has suffered a severe hypoglycemic event will tell you, glucagon is central to energy metabolism. In contrast to what many of us with diabetes may believe, due to lack of beta cells we have dysregulated energy metabolism in general, […]
Saturday Morning Research Review – May 21, 2016
The open-source movement to improve continuous glucose monitoring (CGM) technology by Adam Burrack, PhD As more and more folks become fluent in the programming languages, and as diabetes technology continues to inch into the 21st century, groups like the open-source CGM project are popping up. This group is part of a recent interesting trend to […]
Saturday Morning Research Review – May 7, 2016
Feedback from health care teams improves health outcomes by Adam Burrack, PhD A core tenet of our mission at YOUglycemia is to improve diabetes management through exercise and improved understanding of the biology of how diabetes ‘works’. A corollary of this mission statement is that interaction by our clients – actual dialogue – with experts […]
Saturday Morning Research Review – April 30, 2016
Intensive diabetes management can delay development of diabetic complications by Adam Burrack, PhD One goal of continuous, careful, management of blood glucose levels is the hope that we are delaying the development of diabetes-related complications. A core tenet of our mission at YOUglycemia is that consistent exercise can serve as a pillar of effective diabetes […]
Saturday Morning Research Review – April 23, 2016
Depletion of B cells using anti-CD20 antibody treatment does not reset B cell tolerance by Adam Burrack, PhD We have previously covered the work of Thomas Tedder at Duke University, who studies B cells in the development of type 1 diabetes. As I described in this post from December 2015, one potential method to inhibit […]
Saturday Morning Research Review – April 16, 2016
Exercise science update: 8 exercises for overall strength and 1 method to limit running injuries by Adam Burrack, PhD Our mission at YOUglycemia is to promote improved diabetes management through education and empowerment. We see it as a significant part of our mission to promote aerobic exercise due to the clear benefits in insulin sensitivity, […]
Saturday Morning Research Review – April 9, 2016
Peptide-MHC “nanoparticles” to switch autoreactive T cells to regulatory T cells by Adam Burrack, PhD As I have previously described in our basic science series, regulatory T cells are an important component of the immune system which, in healthy individuals, prevent inappropriate immune responses from developing into autoimmune diseases. In people with type 1 diabetes, […]
Saturday Morning Research Review – April 2, 2016
Physical activity in middle age promotes brain health in old age by Adam Burrack, PhD A core tenet of YOUglycemia’s mission is to promote health throughout the lifespan for people with diabetes, as a step toward mitigating the development of diabetes-related complications. From a recent research report from post-doctoral fellow Dr Nicole Spartano and her […]