Saturday Morning Research Review – July 2, 2016

Promising results of phase 3 clinical trial of islet transplantation to treat hypoglycemia unawareness by Adam Burrack, PhD I’ve previously given an over-view of the state-of-the-art in islet transplantation in my post about the work of James Shapiro and the Edmonton Protocol for immune suppression. In short, prior to the development of strong but non-toxic methods to […]

Saturday Morning Research Review – June 25, 2016

Effects of intense exercise on insulin release and glucose regulation by Adam Burrack, PhD In our “exercise with type 1 diabetes” blog thread, I’ve previously described some of the anti-inflammatory benefits of aerobic exercise for people with type 1 diabetes. As it relates to maximal exercise intensity, the more oxygen we consume at maximum running/cycling […]

Saturday Morning Research Review – June 18, 2016

Runner’s World asks, How Do You Maximize Your Mitochondria? by Daniel Schneider Just 2 weeks ago we pointed to research suggesting that improved mitochondrial function might improve blood glucose management. Improving the quantity and function of the mitochondria is key to endurance athletic performance, but also might be helpful in metabolizing sugar. We used the analogy […]

Saturday Morning Research Review – June 11, 2016

Loss of innervation of pancreatic islets associated with type 1 diabetes but not type 2 diabetes by Adam Burrack, PhD As our readers are aware, type 1 diabetes occurs because beta cells are destroyed by the immune system. This is the basic pathology underlying type 1 diabetes. Since beta cells are the only cells which […]

Saturday Morning Research Review – June 4, 2016

Mitochondrial dysfunction is related to Insulin Resistance in T1 youth. A recent article in the journal Diabetes shows that mitochondrial dysfunction is associated with insulin resistance in youth with type 1 diabetes. This research, conducted by Dr. Melanie Cree Green at the University of Colorado, gives us one more reason to pursue exercise as adjunct therapy for […]

Saturday Morning Research Review – May 28, 2016

The importance of glucagon for blood glucose level maintenance by Adam Burrack, PhD As any diabetic who has suffered a severe hypoglycemic event will tell you, glucagon is central to energy metabolism. In contrast to what many of us with diabetes may believe, due to lack of beta cells we have dysregulated energy metabolism in general, […]

Saturday Morning Research Review – May 21, 2016

The open-source movement to improve continuous glucose monitoring (CGM) technology          by Adam Burrack, PhD As more and more folks become fluent in the programming languages, and as diabetes technology continues to inch into the 21st century, groups like the open-source CGM project are popping up. This group is part of a recent interesting trend to […]

Saturday Morning Research Review – May 7, 2016

Feedback from health care teams improves health outcomes by Adam Burrack, PhD A core tenet of our mission at YOUglycemia is to improve diabetes management through exercise and improved understanding of the biology of how diabetes ‘works’. A corollary of this mission statement is that interaction by our clients – actual dialogue – with experts […]

Saturday Morning Research Review – April 30, 2016

Intensive diabetes management can delay development of diabetic complications by Adam Burrack, PhD One goal of continuous, careful, management of blood glucose levels is the hope that we are delaying the development of diabetes-related complications. A core tenet of our mission at YOUglycemia is that consistent exercise can serve as a pillar of effective diabetes […]

Saturday Morning Research Review – April 23, 2016

Depletion of B cells using anti-CD20 antibody treatment does not reset B cell tolerance by Adam Burrack, PhD We have previously covered the work of Thomas Tedder at Duke University, who studies B cells in the development of type 1 diabetes. As I described in this post from December 2015, one potential method to inhibit […]